Join the teams behind the Paris Biofoundry!
At the Paris Biofoundry, we are pioneering the future of synthetic biology through cutting-edge research, innovation, and collaboration.
Our mission is to tackle global challenges in health, sustainability, and industry by engineering advanced biological systems.
If you’re passionate about biotechnology and eager to make an impact, explore our current job opportunities and become a part of our dynamic, interdisciplinary team.
Biologist Engineer – Cell Engineering and Automation
Fixed-term contract (18 months, renewable)
Education: Master’s degree (or engineering degree) in Cell Biology, Molecular Biology, Biotechnology, or a related field.
Desired Experience: at least 2 to 3 years in a research lab or technology platform
Salary: According to experience
Start Date: As soon as possible
This position is based in the Mammalian Biofoundry at Institut Curie (IC). This platform is a key part of the Paris Biofoundry, a collaborative initiative that aims to speed up synthetic biology in the Île-de-France region. The Mammalian Biofoundry focuses on cell line engineering and phenotyping.
The successful candidate will work under the supervision of Pascal Hersen (Director of the IC Biofoundry) and in close collaboration with Elaine Del Nery (Head of the BioPhenics platform) and Mathieu Coppey (Head of the Molecular and Cellular Biology facility of UMR168). The candidate will work closely with the three members of the robotics platform (automation of cell culture and transfection), as well as with the two engineers of the UMR168 molecular and cellular biology facility (production of plasmids and working cell lines). This recruitment is part of the ramp-up phase of the activities at Institut Curie.
Main duties :
The main purpose of this role is to set up a high-throughput production activity for stable cell lines, ensuring a smooth pipeline between the DNA Biofoundry (Sorbonne) and the Mammalian Biofoundry (Curie).
The engineer will act as an interface with project teams to understand each project’s needs and translate them into protocols for cell line production.
Main activities include:
- Cell engineering and high-throughput production:
- Adapt and optimize culture and transfection conditions for a wide range of mammalian cell lines.
- Design and implement plasmid transfection protocolmarge-tests (lipofection, electroporation) at robotic scale.
- Operate and program robotic liquid-hanmarge-testdling systems (Hamilton) and acoustic transfer technologies for transfection and fluid handling.
- Define and apply selection protocols (antibiotic resistance, flow cytometry sorting) and isolate monoclonal clones, then expand them.
- Characterisation, imaging and analysis (high-content screening):
- Validate generated clones using confocal cell imaging approaches (high-content screening).
- Characterize produced cell lines by confocal microscopy and flow cytometry to ensure insert stability and functionality.
- Ensure full traceability of the process and analyse data from imaging and quality controls.
- Activity management and platform operations
- Be responsible for maintaining, characterising and cryopreserving cell lines.
- Write and update standard operating procedures (SOPs) to ensure reproducible high-throughput work.
- Manage stocks of consumables needed for cell culture and follow preventive maintenance of shared equipment (incubators, biosafety cabinets).
Role specifics :
- Focus: high-throughput cell engineering and robotic automation (confocal microscopy, robotics) to support complex cell-model development.
- Work environment: frequent collaboration with DNA Biofoundry teams; biosafety level 2 lab; intensive use of Hamilton/acoustic transfer robotics and automated confocal microscopy (ImageXpress.ai).
Required skills and qualities
Technical knowledge:
- Strong skills in transfection and cell culture, including creating stable and monoclonal lines (limiting dilution, flow cytometry/FACS sorting).
- Hands-on experience with automated liquid-handling systems is required.
- Skills in molecular biology, confocal microscopy and image analysis are an advantage.
- Good scientific and numerical basics (molarity calculations, concentration normalisation, serial dilutions).
Required abilities:
- Organisation and attention to detail: essential to ensure full traceability of cell banks and to manage several projects in parallel.
- Autonomy: ability to optimise protocols independently and solve technical problems (troubleshooting).
- Team spirit: ability to work in a collaborative multi-site environment (Curie/Sorbonne interface) and report progress clearly.
- Awareness of timelines and quality requirements typical of a service and research-technology platform.
Contact
Please send your application (CV + cover letter + references) by clicking here.
Location : 26 rue d’Ulm 75248 Paris cedex 05 – France
Finance and administration officer
Fixed-term contract (2 years, renewable)
Education: Master’s degree in european affairs, finance, public administration, management / business administration or economics
Desired Experience: all profiles welcome
Salary: According to experience
Start Date: From April 1, 2026 (negotiable)
Missions:
The Finance & Administration Officer will be responsible for supporting the financial, administrative, and operational management of the Paris Biofoundry, a large-scale research infrastructure dedicated to automated bioengineering and synthetic biology. The position will play a key role in ensuring the efficient management of institutional and European funding, including EU FEDER projects, and in supporting the strategic and operational development of the biofoundry.
The successful candidate will work in close collaboration with the management team, scientific coordinators, and institutional partners to ensure compliance with financial regulations, funding requirements, and reporting obligations.
Job Requirements :
- Manage the financial and administrative aspects of national and European-funded projects, including EU FEDER programs, in compliance with applicable regulations and funding guidelines.
- Monitor project budgets, track expenditures, and ensure proper allocation of financial resources.
- Prepare financial reports, budget forecasts, and supporting documentation for funding agencies and institutional partners.
- Coordinate with internal administrative services (finance, HR, procurement) and external stakeholders to ensure smooth project execution.
- Support the preparation and submission of funding applications, amendments, and contractual documents.
- Ensure compliance with institutional, regional, national, and European administrative and financial procedures.
- Contribute to the development and improvement of internal financial and administrative processes.
- Support audits, controls, and evaluations related to funded projects.
- Participate in activity reporting and contribute to strategic planning documents for the Paris Biofoundry.
- Languages: Fluent in French and English.
Contact:
Please send your application (CV + cover letter + references) to:
sciences-biofonderie-direction@sorbonne-universite.fr
Location : Campus Pierre et Marie Curie, Building B – 2nd floor, 4 place Jussieu, 75005 Paris
Bioinformatics Engineer
Education: Master degree in bioinformatics
Desired Experience: all profiles welcome
Salary: According to experience
Start Date: From April 1, 2026 (negotiable)
Missions:
The Engineer in Bioinformatics will support data analysis, pipeline development, and computational workflows associated with high-throughput synthetic biology and bioengineering activities at the Paris Biofoundry. The position will contribute to the design, implementation, and optimization of bioinformatics pipelines for the management, analysis, and integration of large-scale experimental datasets generated by automated DBTL (Design–Build–Test–Learn) workflows.
The successful candidate will work closely with experimental scientists, automation engineers, and data scientists to enable data-driven optimization of bioengineering processes.
Job Requirements :
- Design, develop, and maintain bioinformatics pipelines for the analysis of high-throughput synthetic biology data (genomics, phenotyping, omics, automation-generated datasets).
- Support data integration across DBTL workflows, including metadata management and data traceability.
- Collaborate with experimental teams to define data analysis strategies aligned with project objectives.
- Implement computational tools for data visualization, quality control, and performance monitoring of automated workflows.
- Contribute to the development of standardized data formats and best practices for data management within the Biofoundry.
- Support the deployment of machine learning and data-driven approaches in collaboration with relevant experts.
- Document pipelines, workflows, and analysis methods, and contribute to reporting and dissemination activities.
- Participate in technology watch activities related to bioinformatics, data science, and computational biology.
- Languages: Fluent in French and English.
Contact:
Please send your application (CV + cover letter + references) to:
sciences-biofonderie-direction@sorbonne-universite.fr
Location : Campus Pierre et Marie Curie, Building B – 2nd floor, 4 place Jussieu, 75005 Paris
Spontaneous Applications
The Paris Biofoundry is always eager to meet talented and passionate individuals interested in advancing the field of synthetic biology. If you don’t see a specific role that matches your expertise or are interested in an internship, we welcome spontaneous applications. Our collaborative ecosystem spans DNA assembly, cell-free systems, mammalian cell engineering, and large-scale bioproduction—providing diverse opportunities for those enthusiastic about innovative research and biotechnological development.
If you would like to submit a spontaneous job or internship application, please send us your CV and cover letter detailing your area of interest through the email address indicated on our “Contact Us” page.